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Oligodendrocyte progenitors identified in situ in sections of mouse CNS by immunolabeling for NG2 chondroitin sulfate proteoglycan (red Cy3) and platelet-derived growth factor alpha receptor (green FITC), with overlap appearing yellow. DAPI staining of chromosomes (blue) reveals nuclear changes for detection of progenitors in interphase (top) and progressive stages of mitotis (in decending order), indicative of proliferation in situ.
Both secondary antibodies are Jackson ImmunoResearch products.
Image contributed by Regina Armstrong, Ph.D., Director, Neuroscience Program, Professor, Dept of Anatomy, Physiology, and Genetics, Uniformed Services University of the Health Sciences.