Jackson Immuno Research Inc.
specializing in secondary antibodies and conjugates

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Secondary Antibodies

For VHH Discovery

Anti-Alpaca IgG, Subclass and VHH domain secondaries
  • Ideally time PBMC harvest
  • Enhance detection of VHH antibodies
  • Test for VHH expression and binding activity

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Whole IgG Affinity-Purified Secondary Antibodies

"I have used a wide variety of secondaries and Jackson ImmunoResearch has consistently been the best. The fluorophores are bright and stable and their selective (x reactivity removed) secondaries have always shown species specificity in multiple labeling."

Janet Duerr, Ohio University

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Alpaca Secondary Antibodies

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tech@jacksonimmuno.com

Alpaca Secondary Antibodies

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Alpaca Anti-Human, Anti-Mouse, and Anti-Rabbit Secondary Antibodies

Alpaca

Jackson ImmunoResearch continues to expand our comprehensive range of high quality secondary antibodies for the life science community.

The latest addition to our catalog is a new host species, Alpaca. This presents a new option when goat or donkey secondaries may not be preferable, for example in a multiple labeling assay which has potential unwanted cross-reactions. Secondary antibodies produced in alpaca exhibit inherent minimal cross-reactivity with camelid-derived antibodies (e.g. VHH antibodies, single domain antibodies, nanobodies†).

Alpacas are part of the camelid family, along with llamas and camels. JIR’s affinity purified polyclonal antibodies produced by alpacas are predominantly IgG1 (the conventional subclass featuring both heavy and light chains) and have binding properties that are similar to those derived from the more familiar host species. These antibodies also include the heavy chain only subclasses IgG2 and IgG3.

Learn more about camelid immunoglobulins.

JIR’s alpaca secondary antibodies are prepared to ensure minimal cross-reactivity with bovine serum proteins to avoid background from BSA blocking steps and cell culture components. Further cross-adsorptions enable multiple labeling with the other available target species as shown below.

Read more about multiple labeling protocols.


Available Alpaca Secondary antibodies

  • Alpaca Anti-Human IgG (H+L) (min X Bov, Ms, Rb Sr Prot)
  • Alpaca Anti-Mouse IgG (H+L) (min X Bov, Ms, Rb Sr Prot)
  • Alpaca Anti-Rabbit IgG (H+L) (min X Bov, Ms, Rb Sr Prot)

View all conjugate options


Normal Alpaca Serum is available for blocking

Normal Alpaca Serum Fill Size
028-000-001 2.0 ml
028-000-121 10.0 ml

Learn more about the general principles of blocking and controls in our guide.


†Nanobody and nanobodies are registered trademarks of Ablynx N.V.

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